7 research outputs found

    Will Security and Privacy Updates Affect Users’ Privacy Choices of Mobile Apps

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    There is a growing emphasis among users on safeguarding personal privacy and authorization for applications. To address this, Security and Privacy Updates (SPU) are employed to bolster app security, alleviate user apprehensions regarding security, and encourage users to share data and permissions with greater confidence. Based on the Protection Motivation Theory (PMT), we propose that SPU, an IT technology itself, has a dual effect on users’ privacy choices, security threat susceptibility and security response efficacy are the two key mediators to explain this phenomenon, and that this influencing process will be moderated by user’s privacy trade-off. We will investigate this process through a set of online experiments

    Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA

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    Abstract Adenosine-to-inosine tRNA-editing enzyme has been identified for more than two decades, but the study on its DNA editing activity is rather scarce. We show that amphioxus (Branchiostoma japonicum) ADAT2 (BjADAT2) contains the active site ‘HxE-PCxxC’ and the key residues for target-base-binding, and amphioxus ADAT3 (BjADAT3) harbors both the N-terminal positively charged region and the C-terminal pseudo-catalytic domain important for recognition of substrates. The sequencing of BjADAT2-transformed Escherichia coli genome suggests that BjADAT2 has the potential to target E. coli DNA and can deaminate at TCG and GAA sites in the E. coli genome. Biochemical analyses further demonstrate that BjADAT2, in complex with BjADAT3, can perform A-to-I editing of tRNA and convert C-to-U and A-to-I deamination of DNA. We also show that BjADAT2 preferentially deaminates adenosines and cytidines in the loop of DNA hairpin structures of substrates, and BjADAT3 also affects the type of DNA substrate targeted by BjADAT2. Finally, we find that C89, N113, C148 and Y156 play critical roles in the DNA editing activity of BjADAT2. Collectively, our study indicates that BjADAT2/3 is the sole naturally occurring deaminase with both tRNA and DNA editing capacity identified so far in Metazoa

    Densely interconnected porous BN frameworks for multifunctional and isotropically thermoconductive polymer composites

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    Ideal materials for modern electronics packaging should be highly thermoconductive. This may be achieved through designing multifunctional polymer composites. Such composites may generally be achieved via effective embedment of functional inorganic fillers into desirable polymeric bodies. Herein, two types of high-performance 3D h-BN porous monoliths (3D-BN), namely, h-BN nanorod-assembled networks and nanosheet-interconnected frameworks, are successfully created via an in-situ carbothermal reduction substitution chemical vapor deposition using carbon-based nanorod-interconnected networks as monolithic templates. These 3D-BN porous materials with densely-interlinked frameworks, excellent mechanical robustness and integrity, highly-isotropous and multiple heat transfer paths, enable reliable fabrications of diverse 3D-BN/polymer porous composites. The composites exhibit combinatorial multi-functional properties, such as excellent mechanical strength, light weight (body densities dropped by ~ 5.8 - 24% relative to blank polymers), ultra-low coefficient of thermal expansion (reduced by ~ 66 - 87 % as compared with bare polymers), highly isotropic thermal conductivities (~ 26 - 51 multiples of pristine polymers), relatively low dielectric constants and super-low dielectric losses, and high resistance to softening at elevated temperatures. In addition, the regarded 3D-BN frameworks are easily recycled from their polymer composites, and may be reliably reutilized for multifunctional reuse. Thus, these materials should be valuable for new-era advanced electronic packaging and related applications

    Densely Interconnected Porous BN Frameworks for Multifunctional and Isotropically Thermoconductive Polymer Composites

    No full text
    Ideal materials for modern electronics packaging should be highly thermoconductive. This may be achieved through designing multifunctional polymer composites. Such composites may generally be achieved via effective embedment of functional inorganic fillers into desirable polymeric bodies. Herein, two types of high-performance 3D h-BN porous monoliths (3D-BN), namely, h-BN nanorod-assembled networks and nanosheet-interconnected frameworks, are successfully created via an in-situ carbothermal reduction substitution chemical vapor deposition using carbon-based nanorod-interconnected networks as monolithic templates. These 3D-BN porous materials with densely-interlinked frameworks, excellent mechanical robustness and integrity, highly-isotropous and multiple heat transfer paths, enable reliable fabrications of diverse 3D-BN/polymer porous composites. The composites exhibit combinatorial multi-functional properties, such as excellent mechanical strength, light weight (body densities dropped by ~ 5.8 - 24% relative to blank polymers), ultra-low coefficient of thermal expansion (reduced by ~ 66 - 87 % as compared with bare polymers), highly isotropic thermal conductivities (~ 26 - 51 multiples of pristine polymers), relatively low dielectric constants and super-low dielectric losses, and high resistance to softening at elevated temperatures. In addition, the regarded 3D-BN frameworks are easily recycled from their polymer composites, and may be reliably reutilized for multifunctional reuse. Thus, these materials should be valuable for new-era advanced electronic packaging and related applications
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